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| 1951 |
| | | The new Iranian prime minister, Mohammed Mossadegh, passes the Oil Nationalization Act, seizing Britain's assets in the region | |
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| 1953 |
| | | The first Soviet hydrogen bomb is successfully tested at the Semipalatinsk Test Site in Kazakhstan | |
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| 1953 |
| | | The Iranian prime minister Mohammed Mossadegh is removed from office in an armed coup sponsored by the CIA and Britain's MI6 | |
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| 1962 |
| | | Ruhollah Khomeini, a leading ayatollah in Qom, denounces the Shah of Iran and declares a fatwa against his regime | |
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| 1963 |
| | | Ayatollah Khomeini is arrested in Qom, and imprisoned for eight months in Tehran, after instigating riots against the Shah | |
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| 1964 |
| | | Ayatollah Khomeini, exiled by the shah from Iran, moves first to Turkey and then makes his base in Iraq | |
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| 1965 |
| | | Zahir Shah allows the first elections in his kingdom of Afghanistan | |
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| 1973 |
| | | A military coup deposes Zahir Shah and brings to an end the hereditary monarchy in Afghanistan | |
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| 1978 |
| | | Demonstrations take place throughout Iran, demanding Islamic rule under the leadership of Ayatollah Khomeini | |
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| 1979 |
| | | An Islamic revolution forces the Shah, Mohammad Reza Pahlavi, to flee from Iran | |
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